ABSTRACT
@#<b>Objective</b> To evaluate the clinical significance of transvaginal color Doppler ultrasound for the differential diagnosis of benign and malignant ovarian cysts. <b>Methods</b> Patients who were diagnosed with clinically suspected or palpable adnexal masses and underwent gray-scale ultrasonography, transvaginal color Doppler ultrasonography, and ultrasound-guided fine-needle aspiration cytology (FNAC) during the period from 2018 to 2021 were enrolled in this study. The pulsatility index (<i>PI</i>) and resistance index (<i>RI</i>) were estimated, and an ovarian cyst with the lowest <i>PI</i> value of < 1.0 or the lowest <i>RI</i> value of < 0.4 was considered as malignant. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of gray-scale ultrasound and transvaginal color Doppler ultrasound for the differential diagnosis of benign and malignant ovarian cysts were estimated with FNAC as the gold standard. <b>Results</b> A total of 180 patients with ovarian cysts were recruited, and FNAC revealed that 81 of them had malignant lesions and 99 of them had benign lesions. The transvaginal color Doppler ultrasonograms showed that 75 patients (92.59%) with malignant lesions had blood-flow signals in their cysts and 42 patients (42.24%) with benign lesions had blood-flow signals in their cysts, with a significant difference in the proportion between the two groups (<i>χ</i><sup>2</sup> = 49.29, <i>P</i> < 0.01). Among the 75 patients with blood-flow signals in malignant ovarian cysts, 75 had <i>PI</i> < 1.0 and 24 had <i>RI</i> < 0.4; among the 42 patients with blood-flow signals in benign ovarian cysts, 15 had <i>PI</i> < 1.0 and no one had <i>RI</i> < 0.4; there were significant differences in the proportions of <i>PI</i> < 1.0 and <i>RI</i> < 0.4 between the two groups (<i>χ</i><sup>2</sup> = 62.68, <i>P</i> < 0.01; <i>χ</i><sup>2</sup> = 16.91, <i>P</i> < 0.01). In addition, compared with the combination of gray-scale ultrasound and transvaginal color Doppler ultrasound, gray-scale ultrasound alone had significantly lower sensitivity (51.85% <i>vs</i> 81.48%; <i>χ</i><sup>2</sup> = 16.00, <i>P</i> < 0.01), specificity (75.76% <i>vs</i> 93.94%; <i>χ</i><sup>2</sup> = 12.73, <i>P</i> < 0.01), PPV (63.64% <i>vs</i> 91.67%; <i>χ</i><sup>2</sup> = 15.90, <i>P</i> < 0.01), and NPV (65.79% <i>vs</i> 86.11%; <i>χ</i><sup>2</sup> = 12.44, <i>P</i> < 0.01) for the differential diagnosis of benign and malignant ovarian cysts. <b>Conclusion</b> Gray-scale ultrasound is effective for diagnosing ovarian cysts; however, gray-scale ultrasound combined with transvaginal color Doppler ultrasound can improve the differential diagnosis of benign and malignant ovarian cysts.
ABSTRACT
Objective To evaluate the characteristics of the haemodynamics of the hysteromyoma and its diagnosis value. Methods To apply the transvaginal color doppler ultrasound to detect the blood flow parameters of the uterine artery and the muscular tumor’s peripheral and inner area from 68 patients with hysteromyoma, compared with the blood flow parameters of the uterine artery from 50 normal women so as to analyze their difference. Results (1) In the hysteromyoma group, the maximum blood flow velocity during the systolic phase (SP) and the minimum blood flow velocity during the end-diastolic phase (ED) of uterine artery are significantly higher than those in the normal group(P
ABSTRACT
Objective To investigate the clinical value and sonographic features of locally advanced cervical carcinoma using transvaginal color Doppler ultrasound(TVCDU). Methods A retrospctive analysis was carried on 2-D sonograms. And color Doppler flow imaging(CDFI) in 106 cases, confirmed by pathology and surgery. Results In locally advanced cervical carcinoma, the characteristerics on TVCDU were cervical enlargment, cervical masses accompanying with uteral effusion and extracervical infiltrative masses.The rich cervical blood flow signals demonstrated as called “fireball" sign. In early cervical carcinoma,the cervix showed no apparent cervical enlargment. The blood flow signals were increased.The average RI was 0.41. Conclusions TVCDU which is very valuable in judging the infiltration extent and in differential diagnosis preoperatively can be used as a routine examination method before locally advanced cervical carcinoma treatment.
ABSTRACT
This study was performed to assess whether measurement of uterine artery blood flow impedance(the pulsatility index[PI] and resistance index [RI]) as determined by transvaginal color Doppler ultrasound on the day of oocyte retrieval in patients undergoing in vitro fertilization (IVF) can predict successful pregnancy. From August 1995 to January 1997, ninety-two infertile women with tubal or peritoneal factor infertility who had undergone IVF during controlled ovarian hyperstimulation(COH) cycles were allocated to the study group. The COH using luteal long protocol of GnRH agonist was used in all patients. Transvaginal color Doppler assessment of uterine artery blood flow impedance(PI and RI) on the day of oocyte retrieval was done. When the patients were grouped into pregnant(n=31) and nonpregnant(n=61), the mean value of PI and RI of the nonpregnant group were significantly higher than those of the pregnant group(2.86+/-0.62 vs 2.47+/-0.35 and 0.88+/-0.05 vs 0.85+/-0.04). The patients were also grouped according to whether the PI was low(1.00 to 1.99), medium(2.00 to 2.99), or high(>or=3.00). The pregnancy rate were 33.3%, 44.8% and 10.7% for the low, medium, and high PI groups, respectively, and the pregnancy rate of the medium PI group was significantly higher than that of high PI group. The embryo implantation rates were 11.5%, 15.2% and 4.0% for the low, medium, and high PI groups, respectively, and the implantation rate of medium PI group was significantly higher than that of the high PI group, too. There was no correlation between the mean PI and RI value and serum E2 concentration on the day of hCG administration, or endometrial thickness measured on the day of oocyte retrieval. In conclusion, we fond that the measurements of uterine artery blood flow impedance(PI and RI) on the day of oocyte retrieval might predict subsequent pregnancy and implantation rates and also contribute much to effective management of infertile couples.